Amitriptyline is used for treating depression. Amitriptyline is a tricyclic anti-depressant. How tricyclic antidepressants are thought to increase the action of particular chemicals in the brain (norepinephrine, serotonin), which help improve mood.
Use Amitriptyline as instructed by your doctor.
Elavil can be taken with foods or on an empty abdomen.
Prevent consuming grapefruit or drinking grapefruit juice while taking Amitriptyline.
Amitriptyline might take up to 30 days to manage symptoms of depression. Carry on using Amitriptyline even if you feel great. Do not miss any dose.
Take it as as soon as you can, in the event you skip a dose of Elavil. If it's almost time for your next dose, omit the missed dosage and go back to your usual dosing schedule. Do not take more than one dose at once.
Ask your physician any questions that might have concerning how to use Amitriptyline.
Don't use Amitriptyline if:
you are hypersensitive to any ingredient in Amitriptyline
You're currently using or have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine, selegiline) within the last 14 days
you are using antihistamines (eg, diphenhydramine), cisapride, droperidol, a ketolide (eg, telithromycin), a macrolide (eg, erythromycin), mibefradil, or pimozide
You're dealing with a heart-attack.
Contact your doctor or health care provider immediately if one of these apply to you.
Some medical conditions may interact with Amitriptyline. Tell your doctor or pharmacist if you got any health conditions, particularly if any of the following apply to you:
if you are pregnant, intending to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
When you have a history of mental illness (eg, bipolar disorder, mania, manic-depression), or have considered or tried suicide
When you have glaucoma, an irregular pulse, heart disease, chest pain, liver disease, prostate problems, thyroid disorder, or are unable to urinate (urinary retention)
For those who have a history of seizures, epilepsy, or porphyria.
Some medications may interact with Elavil. Communicate to your doctor should you be getting any other medications, particularly the following:
MAOIs (eg, phenelzine, selegiline) because they may cause serious, sometimes life-threatening, responses. Don't take MAO inhibitors with, or within 14 days of getting Amitriptyline
Anticholinergics (eg, scopolamine), bupropion, cimetidine, fluconazole, phenothiazines (eg, chlorpromazine), SSRIs (eg, fluoxetine), terbinafine, or valproic acid because side effects such as blurred vision, difficult urination, drowsiness or sedation, dry mouth, or lightheadedness may occur
Antihistamines (eg, diphenhydramine), cisapride, droperidol, ketolides (eg, telithromycin), macrolides (eg, erythromycin), mibefradil, pimozide, or streptogramins (eg, quinupristin/dalfopristin) because serious side effects on the heart (eg, racing heartbeat, dizziness, fainting, life-threatening strange heartbeat leading to unconsciousness, and lack of heartbeat, may be increased by Amitriptyline
Carbamazepine, thyroid medicines (eg, synthroid), or stimulants (eg, albuterol, pse) because their negative effects might be raised by Amitriptyline
Warfarin because side effects such as serious bleeding may be raised by Amitriptyline
Clonidine, guanethidine, or guanfacine because the potency of these medicines may be reduced.
This might not be a complete record of all interactions that may happen. Ask your doctor if Amitriptyline may interact with other medicines that you take. Check with your physician before you start, stop, or adjust the dosage of any medication.
Important safety tips:
Elavil may cause dizziness, drowsiness, or blurred vision. Don't drive, operate machinery, or do other things which could be dangerous until you know how you react to Amitriptyline. Utilizing Amitriptyline only, with other medications, or with alcohol may reduce your ability to drive or perform other potentially hazardous tasks.
Prevent drinking alcohol or taking other medicines which cause drowsiness (eg, sedatives, tranquilizers) while taking Elavil. Amitriptyline may add to the consequences of alcohol and other depressants. Request your druggist if you have questions regarding which medicines are depressants.
Elavil can cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may raise these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of these outcomes.
Uncontrollable and unconscious movements may develop in patients using Amitriptyline. Happening is maximum among the aged, particularly girls. The danger of developing these involuntary actions and the odds they'll become permanent are raised with long-term use and with high dosages. Yet, it is possible to create these symptoms after short term use at low dosages. Get in touch with your doctor immediately if any of the following happen: involuntary movements of the tongue, face, mouth, or jaw (eg, protrusion of tongue, smoking of cheeks, puckering of mouth, chewing actions), occasionally accompanied by involuntary movements of the legs and arms.
Amitriptyline may cause sensitivity to sunlight. Avoid prolonged exposure to sunlight and other ultra-violet light (eg, tanning beds). Use sunscreens and wear protective clothing until tolerance is established.
Do not become overheated in hot climate or during exercise or other activities since heatstroke may occur.
Diabetes patients - Amitriptyline might change your blood glucose. Check blood sugar levels closely. Ask your doctor before changing the dose of your diabetes medication.
Before you have any medical or dental remedy, emergency treatment, or surgery, inform the physician or dentist that you're using Amitriptyline.
Use care in the elderly; they may be more sensitive to the effects, specially lightheadedness upon standing; swift pulse; breathing problems; hard urination; and constipation.
Maternity and breast - feeding: If you plan on becoming pregnant, discuss with your doctor the benefits and dangers of using Amitriptyline while pregnant. Elavil is excreted in the breast milk. Do not breastfeed while taking Elavil.

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