Depakote is used when treating numerous kinds of seizure problems. It's occasionally used as well as other seizure medicines. It's also used in the treatment of the manic stage of bipolar disorders (manic depressive illness), and to prevent migraine headaches. Depakote impacts chemicals in the human body that might be involved in causing convulsions.
Use Depakote as instructed by your doctor.
Take Depakote by mouth with or without any food. Take with food to lower gut discomfort, if stomach upset happens.
Swallow Depakote entire. Do not break, crush, or chew before taking.
Drink lots of water while you are using Depakote. Your dose might need to be altered should you not find sufficient liquids each day.
Do not stop taking Depakote unexpectedly, especially in case you are taking Depakote to stop convulsions. Suddenly stopping Depakote can cause severe seizures to occur. Your doctor will gradually lower your dosage, if you want to stop Depakote.
Taking Depakote simultaneously every day can help you be sure you go on it.
Continue to take Depakote also if you feel well. Don't miss any dose. Depakote works best when there's a constant amount of it in your body.
Go as as soon as you can, in case you miss a dose of Depakote. When it is almost time for your following dose, skip the missed dose and go back to your usual dosing timetable. Do not take more than one dose at once.
Ask your physician any questions that might have regarding the way to use Depakote.
Do NOT use Depakote if:
You're hypersensitive to any ingredient in Depakote
You've got liver problems or even a urea cycle disorder.
Contact your physician or physician immediately if any of these apply to you.
Some health conditions may interact with Depakote. If you hold any medical conditions, especially if any of these apply to you tell your doctor or pharmacist:
If you're pregnant, planning to get pregnant, are breast feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
When you have a history of alcohol misuse, liver difficulties, metabolic disease, blood disease, HIV infection, cytomegalovirus (CMV) infection, high blood levels of ammonia or gln, low body temperatures, low levels of albumin, brain problems (eg, organic brain disease), mental retardation, inflammation of the pancreas, kidney problems, or low levels of white blood cells, or whether you're scheduled for operation
When you have a history of ornithine transcarbamylase deficiency or unexplained coma
When you have a household background of urea cycle disorders or unexplained infant deaths
In case you have a background of mental or mood problems (eg, depression), or suicidal feelings or steps
In the event you take any other medicine for seizures.
Some medications may interact with Depakote. Communicate to your doctor if you are getting any other medications, particularly any of the following:
Benzodiazepines (eg, diazepam), carbamazepine, erythromycin, felbamate, fluoxetine, guanfacine, isoniazid, ketoconazole, risperidone, or salicylates (eg, aspirin) because the risk of significant side effects of Depakote, including changes in vision or other vision issues, clumsiness or unsteadiness, drowsiness, vomiting, or sickness, could possibly be raised
Clonazepam because the danger of convulsions may be increased
Because the chance of large ammonium levels, mind problems, or an uncommon drop in body temperature may be increased topiramate
Aciclovir, cancer medicines, carbapenem antibiotics (eg, ertapenem, imipenem, meropenem), cholestyramine, hydantoins (eg, phenytoin), mefloquine, nonsteroidal anti inflammatory drugs (NSAIDs) (eg, ibuprofen), oral contraceptives (eg, oral contraceptives), or rifampin because they might fall Depakote's effectiveness
Anticoagulants (eg, warfarin), barbiturates (eg, phenobarbital), ethosuximide, lamotrigine, methylphenidate, primidone, tolbutamide, tricyclic antidepressants (eg, amitriptyline), or zidovudine because the chance of the side effects may be increased by Depakote.
This might not be a complete list of all relationships that may happen. Ask your doctor if Depakote may interact with several other medicines which you take. Check with your health care provider before you begin, stop, or adjust the dosage of any medicine.
Important security tips:
Depakote may cause drowsiness, dizziness, or blurred vision. These effects might be worse for it with alcohol or specific medicines. Use Depakote with warning. Do not drive or execute other potential unsafe jobs until you realize how you react to it.
Don't drink alcohol or use medications that might cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Depakote; it might enhance their results. Ask your pharmacist if you've got questions about which medicines may cause drowsiness.
Irritation of the pancreas is a potentially deadly illness associated with Depakote. Symptoms include stomach pain, nausea, or lack of appetite. Contact your doctor right away if any of these signs occur.
Sufferers who take Depakote could be at increased risk for suicidal thoughts or actions. The risk may be greater in patients who have had suicidal thoughts or actions in the recent past. Individuals who have bipolar (manicdepressive) sickness might also have an increased risk for suicidal thoughts or actions. Observe sufferers who take Depakote closely. Contact the physician at the same time if new, worsened, or unexpected symptoms, such as depressed mood; uneasy, unsettled, irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor immediately if any indications of suicidal thoughts or actions happen.
Depakote might reduce the number of clotforming cells (platelets) in your blood. Prevent activities that may lead to bruising or injury. Tell your doctor if you have uncommon bruising or bleeding. Tell your physician when you've got dark, tarry, or bloody stools.
Tell your doctor or dentist that you just take Depakote before you obtain any medical or dental treatments, emergency care, or operation.
Diabetes patients - Depakote can cause the results of some s for urine ketones to be wrong. Ask your doctor before changing your diet or the dosage of your diabetes medicine.
Depakote may increase the ammonia levels in your bloodstream. Contact your doctor immediately in case you experience unexplained slowness and vomiting or mental changes.
Depakote may cause an unusual drop in body temperature (hypothermia). Signs could include confusion, lack of energy, loss of control, shivering, slow pulse, slow or shallow breathing, slurred speech, or unusual drowsiness. Contact your physician immediately if you've got any of the symptoms.
Depakote might interfere with specific lab s, including thyroid function. Make sure your physician and lab personnel know you are taking Depakote
While you use Depakote laboratory s, including complete blood cell counts, blood ammonia levels, and liver function, may be performed. These s might be utilized to monitor your state or check for side effects. Be sure to keep all physician and laboratory appointments.
Use Depakote with caution in the elderly; they might be more sensitive to its effects, especially drowsiness.
Depakote must be used with extreme care in children younger than 10 years old; usefulness and security in these children haven't been validated. Kids younger 2 years might be at higher risk of severe liver problems.
Maternity and breastfeeding: Depakote was shown to cause injury to the fetus. Use a highly effective form of birth-control while you take Depakote. If you think you might be pregnant or when you wish to get pregnant, contact your doctor. While you are pregnant you're going to need to talk about the benefits and dangers of using Depakote. Depakote can be found in breast milk. Don't breast-feed as you are taking Depakote.

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